1 00:00:07,073 --> 00:00:09,974 AII right, hold on. I got the turn up here. 2 00:00:11,244 --> 00:00:12,541 (WHOOPING) 3 00:00:18,218 --> 00:00:20,743 Oh! How cool was that? 4 00:00:20,820 --> 00:00:22,651 That was way cool! 5 00:00:27,427 --> 00:00:29,759 My turn. Sorry, that's not allowed. 6 00:00:29,829 --> 00:00:31,694 I just signed 15 pages of forms saying 7 00:00:31,765 --> 00:00:34,859 you gotta ride on the back of that thing. I don't see any Iawyers around. 8 00:00:34,934 --> 00:00:36,925 You know that's not the point. No. 9 00:00:37,003 --> 00:00:39,938 You just wanna keep all the fun to yourself. 10 00:00:40,974 --> 00:00:42,464 Come on, Dad! 11 00:00:43,576 --> 00:00:46,044 You go over 15, we're pulling over, all right? I mean it. 12 00:00:46,112 --> 00:00:48,410 You're the best. AII right, get on there. 13 00:00:48,481 --> 00:00:50,574 Put on your goggles. Okay. 14 00:00:51,518 --> 00:00:53,543 Ready? Got the clutch in? 15 00:00:53,620 --> 00:00:55,645 AII right, that's my boy. 16 00:00:58,425 --> 00:01:00,552 (WHOOPING) 17 00:01:09,402 --> 00:01:12,235 Adam, you're going too fast, slow it down! 18 00:01:15,375 --> 00:01:18,367 I mean it, you're going too fast. SIow down! 19 00:01:18,445 --> 00:01:19,707 Adam! 20 00:01:25,018 --> 00:01:26,110 Adam! 21 00:01:27,754 --> 00:01:29,654 Let go of the throttle! 22 00:01:33,893 --> 00:01:35,019 Adam! 23 00:01:35,395 --> 00:01:37,192 Adam! No! 24 00:02:12,198 --> 00:02:14,689 PARAMEDIC: What've you got? Sixteen-year-old, status post, 25 00:02:14,767 --> 00:02:16,632 ATV crash, 40% burns on his body. 26 00:02:16,703 --> 00:02:18,136 Nasotracheal intubation. 27 00:02:18,204 --> 00:02:19,933 Start a bag of Iactated Ringer's, wide open... 28 00:02:20,006 --> 00:02:22,201 Will he be okay? We'II be with you when we can. 29 00:02:22,275 --> 00:02:23,674 Get him out! 30 00:02:24,043 --> 00:02:25,670 Wait, wait, wait! 31 00:02:25,912 --> 00:02:29,006 NURSE: I'II start fluids. Let's go get him hooked up. 32 00:02:30,817 --> 00:02:32,375 SURGEON: Watch the Iine. 33 00:02:44,230 --> 00:02:45,720 (READING HINDI) 34 00:02:51,104 --> 00:02:53,937 Been Iooking for you. Been avoiding you. 35 00:02:54,174 --> 00:02:55,300 Burn Unit can handle it. 36 00:02:55,375 --> 00:02:58,936 If they could handle it, they wouldn't be asking for you. 37 00:03:00,813 --> 00:03:03,043 Is that a journal? Friend wrote an article. 38 00:03:03,116 --> 00:03:04,276 In Hindi? 39 00:03:04,350 --> 00:03:07,581 They have a cutting-edge neuroscience program in India. 40 00:03:07,654 --> 00:03:09,884 It says so right on the cover. 41 00:03:13,726 --> 00:03:15,853 Kid's heart rate's messed. 42 00:03:15,929 --> 00:03:18,295 Tachycardia can be explained by the burn. 43 00:03:18,364 --> 00:03:20,798 I assume the Burn Unit knew that. 44 00:03:23,136 --> 00:03:24,831 His potassium's Iow. 45 00:03:24,904 --> 00:03:26,838 Which can also be explained by the burn. 46 00:03:26,906 --> 00:03:29,431 Except I'm sure the Burn Unit's pumping him with fluids 47 00:03:29,509 --> 00:03:32,103 which means his potassium should be going up, not down. 48 00:03:32,178 --> 00:03:33,736 Could be amphetamines. 49 00:03:33,813 --> 00:03:35,678 Or bacteria Iunching on his heart. 50 00:03:35,748 --> 00:03:39,081 Or cardiomyopathy, or some other very bad thing. 51 00:03:39,152 --> 00:03:40,779 HOUSE: He needs an EKG. 52 00:03:43,056 --> 00:03:44,045 (EXCLAIMING) 53 00:03:47,760 --> 00:03:50,888 Okay, no skin, no EKG. 54 00:03:50,964 --> 00:03:53,398 CHASE: Is he even gonna survive the burn? 55 00:03:53,566 --> 00:03:55,693 What, you got a date or something? 56 00:03:56,202 --> 00:03:58,363 Forty percent of his body. 57 00:03:58,438 --> 00:04:00,906 If the Burns Unit can prevent an infection, 58 00:04:00,974 --> 00:04:03,033 his body will regenerate maybe 10%, 59 00:04:03,109 --> 00:04:05,873 surgeons will do 20 or so grafts, six months in this room, 60 00:04:05,945 --> 00:04:09,506 he'II end up with a series of nasty scars, maybe some pain, 61 00:04:09,582 --> 00:04:10,981 but he'II Iive. 62 00:04:11,584 --> 00:04:12,983 Unless his heart shuts down 63 00:04:13,052 --> 00:04:17,648 'cause we can't figure out what's causing the Iow potassium and tachycardia. 64 00:04:18,458 --> 00:04:21,859 We need help from a Belgian doc named Einthoven. 65 00:04:21,928 --> 00:04:23,259 He's dead. 66 00:04:23,329 --> 00:04:27,197 While he was alive, he invented a Iittle dittie called the Galvanometer. 67 00:04:27,267 --> 00:04:28,325 Where do we get one? 68 00:04:28,401 --> 00:04:31,962 Go to any electronics store that's been open since before 1905. 69 00:04:32,038 --> 00:04:36,099 There's a good chance they've got one in a corner in the basement. 70 00:04:37,410 --> 00:04:39,844 BRENDA: We need an audio-visual setup for the Iecture hall. 71 00:04:39,912 --> 00:04:41,846 What for? For the Iecture. 72 00:04:41,914 --> 00:04:44,405 What Iecture? Dr. Weber's Iecture. 73 00:04:44,651 --> 00:04:47,984 Who is Dr. Weber? A neurologist, I think. 74 00:04:48,621 --> 00:04:50,521 The memo was from you. 75 00:04:56,863 --> 00:04:59,127 Where is my assistant? She Ieft. 76 00:04:59,198 --> 00:05:00,358 When? Wednesday. 77 00:05:00,433 --> 00:05:02,731 Seriously? Well, the temp agency sent someone, 78 00:05:02,802 --> 00:05:04,064 but she got Iost. 79 00:05:04,137 --> 00:05:06,628 Well, when she gets here, fire her. 80 00:05:27,260 --> 00:05:28,887 Oh, yeah. 81 00:05:28,961 --> 00:05:31,691 Did you issue this memo? Look at that. 82 00:05:33,633 --> 00:05:34,930 Congratulations. 83 00:05:35,001 --> 00:05:37,299 The patient that has been in a coma for two years and counting 84 00:05:37,370 --> 00:05:38,701 is still in a coma. 85 00:05:38,771 --> 00:05:40,500 This is not my signature. 86 00:05:40,573 --> 00:05:42,165 I don't know anything about this guy. 87 00:05:42,241 --> 00:05:45,108 I'm supposed to introduce him? Have Iunch? 88 00:05:46,913 --> 00:05:49,780 The coma patient has a migraine? Oh, no, no, no. 89 00:05:49,849 --> 00:05:52,181 No, I gave him medication to prevent a migraine. 90 00:05:52,251 --> 00:05:53,718 That's a migraine. 91 00:05:53,786 --> 00:05:56,084 Increased flow velocity in his cerebral arteries. 92 00:05:56,155 --> 00:05:58,817 I did subsequently give him nitroglycerin, which could possibly... 93 00:05:58,891 --> 00:06:03,021 You induced a migraine headache in a coma patient? 94 00:06:03,096 --> 00:06:06,759 I gave him a Iittle headache, similar to the one you're giving me now. 95 00:06:06,833 --> 00:06:09,393 Have you even read an ethical guideline? 96 00:06:09,469 --> 00:06:12,438 Well, it would be wrong to try out a new migraine prevention medication 97 00:06:12,505 --> 00:06:14,735 on someone who can actually feel pain. 98 00:06:14,807 --> 00:06:17,901 Did you sign this? Yeah. 99 00:06:19,345 --> 00:06:22,712 We can talk Iater about the appropriate discipline. 100 00:06:26,185 --> 00:06:27,277 CAMERON: Because of the burn, 101 00:06:27,353 --> 00:06:29,821 we can't perform any of our normal tests to see what's wrong. 102 00:06:29,889 --> 00:06:32,483 So we're going to try a Galvanometer. 103 00:06:33,159 --> 00:06:36,322 It picks up a pulse in the wrists and the ankles. 104 00:06:36,662 --> 00:06:39,859 Hopefully it'II tell us why his heart rhythm is abnormal. 105 00:06:39,932 --> 00:06:43,197 What have I done to him? I... It was an accident. 106 00:06:43,903 --> 00:06:45,495 AII right? So... 107 00:06:46,439 --> 00:06:47,770 He's got all these burns 108 00:06:47,840 --> 00:06:50,035 and now there's something wrong with his heart? 109 00:06:50,109 --> 00:06:52,873 We're trying to figure out if the two are somehow connected. 110 00:06:52,945 --> 00:06:55,937 Had he been sick Iately? No, nothing. 111 00:06:56,015 --> 00:06:57,642 Anything unusual with his behavior? 112 00:06:57,717 --> 00:06:59,412 Had he been tired a Iot? Nothing. 113 00:06:59,485 --> 00:07:03,615 He was great, he was happy, he was just having a great time, and then... 114 00:07:03,689 --> 00:07:07,318 If he was experimenting with amphetamines or cocaine... 115 00:07:07,393 --> 00:07:08,451 No. 116 00:07:09,095 --> 00:07:11,825 We gave him some pot about a year ago, to try... 117 00:07:11,898 --> 00:07:13,422 It was just once. 118 00:07:13,499 --> 00:07:16,059 We thought if we took the mystery out of drugs and alcohol, 119 00:07:16,135 --> 00:07:17,466 the Iess he'd experiment. 120 00:07:17,537 --> 00:07:19,869 We'II know more after the tests. 121 00:07:21,774 --> 00:07:24,709 It Iooks Iike they're gonna electrocute him. 122 00:07:25,912 --> 00:07:27,311 PIug it in. 123 00:07:28,815 --> 00:07:30,339 You plug it in. 124 00:07:30,950 --> 00:07:32,884 Fine. Give me the cord. 125 00:07:39,792 --> 00:07:41,020 Works. 126 00:07:43,463 --> 00:07:44,896 Prominent U waves. 127 00:07:44,964 --> 00:07:47,865 No inverted T wave. No ischemia. 128 00:07:48,067 --> 00:07:49,694 Q wave normal. 129 00:07:50,603 --> 00:07:52,230 That's not good. 130 00:07:55,942 --> 00:07:58,274 Okay, turn it off. Turn it off! 131 00:07:58,344 --> 00:08:00,278 What's happening? What is that? 132 00:08:00,346 --> 00:08:01,574 CHASE: The seizure's getting... 133 00:08:01,647 --> 00:08:03,410 Can't you stop that? 134 00:08:09,889 --> 00:08:11,686 Who electrocuted my patient? 135 00:08:11,757 --> 00:08:13,691 He had a seizure. CAMERON: He wasn't electrocuted. 136 00:08:13,759 --> 00:08:16,421 What does the seizure tell us? Move. 137 00:08:16,496 --> 00:08:17,724 What are you Iooking for? 138 00:08:17,797 --> 00:08:21,563 Same as you are, Iove, acceptance, solid return on an investment. 139 00:08:21,634 --> 00:08:23,226 Differential diagnosis. Go. 140 00:08:23,302 --> 00:08:25,202 Could be epilepsy or seizure disorder. 141 00:08:25,271 --> 00:08:28,638 Not with the tachycardia. It could be a virus in his brain. 142 00:08:28,708 --> 00:08:31,006 Your specificity's impressive. 143 00:08:31,077 --> 00:08:32,601 Adrenoleukodystrophy. 144 00:08:32,678 --> 00:08:33,975 Could be MS. 145 00:08:34,046 --> 00:08:36,708 The seizures could be caused by plaques and Iesions on the brain. 146 00:08:36,782 --> 00:08:39,410 Well, Iet's find out which. Get him an MRI. 147 00:08:39,485 --> 00:08:41,248 No nuclear imaging! 148 00:08:43,022 --> 00:08:47,322 He wouldn't survive the move to Radiology. MRI and CT scan are both out. 149 00:08:47,393 --> 00:08:50,624 Okay, Iumbar puncture will tell us if his proteins are elevated, 150 00:08:50,696 --> 00:08:52,027 at Ieast we can exclude MS. 151 00:08:52,164 --> 00:08:54,132 We can't do a Iumbar puncture either. 152 00:08:55,801 --> 00:08:57,860 You're cramping my exits. 153 00:08:57,937 --> 00:08:59,768 Don't tell me, no skin on his spine. 154 00:08:59,839 --> 00:09:02,774 We'd be inserting a needle into an area that's teeming with bacteria. 155 00:09:02,842 --> 00:09:05,675 If he doesn't have a brain infection already, we'd give him one for sure. 156 00:09:05,745 --> 00:09:08,475 There's no other way to Iook at a brain. 157 00:09:09,348 --> 00:09:11,612 Transcranial Doppler Sonography. 158 00:09:11,684 --> 00:09:14,847 She said "brain," not "pregnant woman's uterus." 159 00:09:14,921 --> 00:09:17,685 They do sound alike. I used one to Iook at a brain this morning. 160 00:09:17,757 --> 00:09:20,419 Why didn't you take the patient to Radiology, get an MRA? 161 00:09:20,493 --> 00:09:22,586 Obviously I was doing something illegal. 162 00:09:22,662 --> 00:09:24,926 Using nuclear imaging would have raised questions. 163 00:09:24,997 --> 00:09:27,795 You're not gonna get a diagnosis of MS from a sonogram. 164 00:09:27,867 --> 00:09:29,926 Not definitively, but patients with MS 165 00:09:30,002 --> 00:09:33,096 have more reactive neurons in their occipital cortex. 166 00:09:36,909 --> 00:09:38,240 Okay then. 167 00:09:41,347 --> 00:09:44,282 Thank you for all coming to today's Iecture 168 00:09:44,350 --> 00:09:46,409 by Dr. Phillip Weber, 169 00:09:46,852 --> 00:09:49,480 who is our guest today at our hospital 170 00:09:49,555 --> 00:09:53,082 to talk about headaches. 171 00:09:54,226 --> 00:09:57,957 Dr. Weber is at the Weber Center for Pain, that makes sense. 172 00:09:58,364 --> 00:10:01,162 Weber, Weber. So please welcome Dr. Weber! 173 00:10:08,608 --> 00:10:11,668 Thank you Dr. Cuddy. 174 00:10:11,844 --> 00:10:13,744 (AUDIENCE LAUGHING) 175 00:10:13,913 --> 00:10:17,610 I suppose I should tell you a Iittle bit more about myself. 176 00:10:18,384 --> 00:10:20,682 I went to school in Virginia. 177 00:10:21,687 --> 00:10:23,678 You've never been to one of these things in your Iife. 178 00:10:23,756 --> 00:10:26,281 Who is this guy? No idea. 179 00:10:27,627 --> 00:10:29,527 What's with the outfit? 180 00:10:29,962 --> 00:10:32,760 Sudden chills and Iight sensitivity. 181 00:10:33,165 --> 00:10:34,632 Inexplicable. 182 00:10:35,468 --> 00:10:39,063 I received my medical degree at Johns Hopkins University, 183 00:10:39,505 --> 00:10:42,440 where I studied under Brightman and Gilmar... 184 00:10:42,541 --> 00:10:44,338 Hmm. He must be good. 185 00:10:44,410 --> 00:10:47,436 You went to Hopkins, and studied under Brightman and Gilmar. 186 00:10:47,513 --> 00:10:48,912 Shh. 187 00:10:48,981 --> 00:10:52,382 ...helped me win the Doyle Internship at the Mayo CIinic. 188 00:10:52,451 --> 00:10:55,443 You were supposed to get the Doyle Internship. 189 00:10:57,890 --> 00:11:01,485 This guy's Von Lieberman? The guy who got you thrown out for cheating? 190 00:11:01,560 --> 00:11:05,291 The dean threw me out. Von Lieberman just ratted on me. 191 00:11:05,364 --> 00:11:07,594 This guy's name is Weber, not Von Lieberman. 192 00:11:07,667 --> 00:11:10,864 I call Weber Von Lieberman, way eviler. 193 00:11:11,404 --> 00:11:12,393 Shh. 194 00:11:13,439 --> 00:11:17,535 ...1 D receptors have improved the acute treatment of migraines, 195 00:11:18,411 --> 00:11:19,969 to this point... 196 00:11:20,046 --> 00:11:21,604 So what's the plan? 197 00:11:21,681 --> 00:11:25,242 You gonna wait until he bends over and make a fart sound? 198 00:11:25,484 --> 00:11:29,386 I'm not here about the past. He's a bad scientist. 199 00:11:30,489 --> 00:11:33,424 Well, you cheated off him, how bad can he be? 200 00:11:34,894 --> 00:11:36,862 He got the answer wrong. 201 00:11:44,637 --> 00:11:46,298 DOUG: Are they trying to wake him up? 202 00:11:46,372 --> 00:11:48,602 They can't do that, right? He'II be in too much pain. 203 00:11:48,674 --> 00:11:50,972 Don't worry, he's still under. 204 00:11:51,043 --> 00:11:54,308 But the brain never completely sleeps, it's always working. 205 00:11:54,380 --> 00:11:57,872 Controlling your heart rate, breathing, temperature. 206 00:11:59,051 --> 00:12:01,076 The eyes respond to visual stimuli. 207 00:12:01,153 --> 00:12:03,121 BIood flow increases in certain areas of the brain 208 00:12:03,189 --> 00:12:05,680 and we can track that with a sonogram. 209 00:12:05,758 --> 00:12:10,218 With MS, blood vessels are more reactive, so flow is faster. 210 00:12:10,429 --> 00:12:12,488 If Adam has an infection, 211 00:12:12,665 --> 00:12:15,099 there'd be swelling, which would constrict the arteries. 212 00:12:15,167 --> 00:12:17,397 And the flow would be slower. 213 00:12:17,470 --> 00:12:20,303 Chase. Near the subarachnoid space. 214 00:12:26,612 --> 00:12:30,639 WEBER: Data from control subjects were analyzed of a two-way ANOVA 215 00:12:30,716 --> 00:12:33,810 with status and side as within-subject factors. 216 00:12:35,321 --> 00:12:39,018 You stalked this guy for 20 years just for this shot to humiliate him? 217 00:12:39,091 --> 00:12:41,059 I'm trying to Iearn. 218 00:12:41,127 --> 00:12:43,459 ...vessels without significant rebound... 219 00:12:43,529 --> 00:12:46,191 He doesn't even know what that means. 220 00:12:46,265 --> 00:12:47,732 You're gonna interrupt him, aren't you? 221 00:12:47,833 --> 00:12:49,425 If I have a question. 222 00:12:49,502 --> 00:12:51,470 And what's that gonna accomplish? 223 00:12:51,537 --> 00:12:55,303 Why can't you just enjoy this? Why can't you just be happy for me? 224 00:12:55,374 --> 00:12:59,708 You have got to find Iess debilitating outlets than humiliating people. 225 00:12:59,779 --> 00:13:03,215 I hear bowling is more fun than stalking. 226 00:13:03,816 --> 00:13:05,306 But I'm better at this. 227 00:13:05,384 --> 00:13:07,852 ...if "P" is Iess than point-zero... 228 00:13:07,920 --> 00:13:10,411 BIow a ton of money on a plasma TV. 229 00:13:11,824 --> 00:13:14,054 We found a subarachnoid bleed. 230 00:13:15,394 --> 00:13:17,862 BIeed in the head isn't causing seizures. 231 00:13:17,930 --> 00:13:21,229 It could be. 10% with damage to cerebral cortex have a seizure. 232 00:13:21,300 --> 00:13:22,858 Or bacterial meningitis. 233 00:13:22,935 --> 00:13:25,165 Viral encephalitis? There's no way to tell without... 234 00:13:25,237 --> 00:13:26,465 Shut up! 235 00:13:27,673 --> 00:13:29,072 Excuse me. 236 00:13:30,342 --> 00:13:31,604 Not you. 237 00:13:31,677 --> 00:13:35,340 You know, if my Iecture is interrupting your meeting, I can wait. 238 00:13:35,414 --> 00:13:36,813 (SPEAKING HINDI) 239 00:13:38,350 --> 00:13:41,342 As your people say in India. Appreciate it. 240 00:13:41,420 --> 00:13:44,981 We'II figure out why Iater. Fix the bleed or he dies. 241 00:13:45,057 --> 00:13:47,287 Talk to you in a couple hours. 242 00:13:49,962 --> 00:13:51,156 (SPEAKING HINDI) 243 00:14:01,440 --> 00:14:03,670 I'm in the subarachnoid space. 244 00:14:04,777 --> 00:14:07,041 Can you get it? Think so. 245 00:14:09,415 --> 00:14:11,406 Put the probe back where it was so I can see the wire! 246 00:14:11,483 --> 00:14:12,575 We're Iooking for the bleed in... 247 00:14:12,651 --> 00:14:16,781 Look when I get there, I'm flying blind without a contrast CT here! 248 00:14:26,031 --> 00:14:30,400 ...and with a p-value of Iess than 0.001, 249 00:14:30,736 --> 00:14:35,105 we have strong statistical evidence that this drug prevents migraine headaches 250 00:14:35,174 --> 00:14:37,540 without daily administration. 251 00:14:38,177 --> 00:14:39,735 Excuse me, Doctor. 252 00:14:39,812 --> 00:14:41,473 He knows his field better than you do. 253 00:14:41,547 --> 00:14:45,506 It's always been my understanding that, unless you follow a daily regimen, 254 00:14:45,584 --> 00:14:47,609 no drug can prevent a migraine. 255 00:14:47,686 --> 00:14:49,586 That's why they call it a breakthrough. 256 00:14:49,655 --> 00:14:51,850 That's why you call it a breakthrough. 257 00:14:51,924 --> 00:14:55,223 No, the pharmaceutical company sponsoring my clinical trials 258 00:14:55,294 --> 00:14:57,524 also hails it as a breakthrough. 259 00:14:57,596 --> 00:15:00,224 I'm sure your wife and Iawyer do, too. 260 00:15:01,467 --> 00:15:03,765 Is there anybody who doesn't stand to make a fortune from it 261 00:15:03,836 --> 00:15:05,303 calling it a breakthrough? 262 00:15:05,371 --> 00:15:06,531 Who are you? 263 00:15:06,605 --> 00:15:09,096 Just a Iunatic who desperately needs a hobby. 264 00:15:09,174 --> 00:15:11,165 How exactly do these studies work? 265 00:15:11,243 --> 00:15:13,177 Do you give this drug to a bunch of people, 266 00:15:13,245 --> 00:15:16,874 and if they don't get a migraine, you go, "Voila, my drug works"? 267 00:15:16,949 --> 00:15:18,541 Excuse me, miss? 268 00:15:18,918 --> 00:15:20,681 Do you have cancer? 269 00:15:22,254 --> 00:15:25,223 Wow! Mango juice prevents cancer. 270 00:15:25,691 --> 00:15:28,888 Perhaps I should have taken my medication before this Iecture. 271 00:15:31,063 --> 00:15:35,397 WEBER: We had a very specific control group, chronic migraine sufferers. 272 00:15:35,467 --> 00:15:37,594 I don't have time to go through all the math right now, 273 00:15:37,670 --> 00:15:41,128 but the incidence was dramatically... Sure, in India. 274 00:15:41,740 --> 00:15:44,402 Two plus two equals five there, right? 275 00:15:45,411 --> 00:15:46,673 Do I know you? 276 00:15:46,745 --> 00:15:50,340 I know your math skills. They blow. 277 00:15:50,916 --> 00:15:52,110 Touche. 278 00:15:52,184 --> 00:15:54,084 You sound very familiar. 279 00:15:54,153 --> 00:15:57,020 Why did you publish it in an obscure journal in India? 280 00:15:57,089 --> 00:16:01,583 Why not publish it in really, really cool head cases of South Philly? 281 00:16:01,660 --> 00:16:04,356 Neuroscience New Delhi is a respected journal. 282 00:16:04,430 --> 00:16:08,093 Yeah. The guy running SIurp N' Gulp tells me it's one of the best. 283 00:16:08,167 --> 00:16:10,101 Get a hooker, anything. 284 00:16:10,169 --> 00:16:13,764 See, I'm thinking that publishing studies is probably the easiest way 285 00:16:13,839 --> 00:16:16,467 to get a pharmaceutical company to give you a reach-around. 286 00:16:16,542 --> 00:16:19,636 And choosing a journal that no one can actually read, well, that's... 287 00:16:19,712 --> 00:16:20,906 That's shrewd. 288 00:16:20,980 --> 00:16:24,746 I know I know you. Sure you do, Dick. 289 00:16:25,217 --> 00:16:26,275 The name's Philip. 290 00:16:26,385 --> 00:16:29,445 My bad. Something to do with your face. 291 00:16:29,521 --> 00:16:31,751 I always think your name is Dick. 292 00:16:31,824 --> 00:16:33,815 House? Here. 293 00:16:35,761 --> 00:16:39,595 Medical school was 20 years ago. Give it a rest. Grow up. 294 00:16:39,665 --> 00:16:44,432 Yeah. You were always the grown-up. Do the responsible thing, tattletale! 295 00:16:44,903 --> 00:16:47,895 You cheated! I cheated then, you're cheating now! 296 00:16:47,973 --> 00:16:49,031 Your drug doesn't work. 297 00:16:49,108 --> 00:16:52,600 Oh, yes, you would Iike to believe that because it plays right into your fantasy... 298 00:16:52,678 --> 00:16:54,669 I tested it. Oh, really? 299 00:16:55,014 --> 00:16:57,949 What are your parameters? Where's your study? 300 00:17:00,452 --> 00:17:02,044 Room 2134. 301 00:17:02,354 --> 00:17:04,652 One patient? The coma patient? 302 00:17:05,924 --> 00:17:07,949 You haven't changed a bit. 303 00:17:08,727 --> 00:17:12,595 You took shortcuts in med school, you're taking shortcuts now. 304 00:17:12,798 --> 00:17:16,063 You cannot test this on an abnormal brain. 305 00:17:16,135 --> 00:17:20,162 That's so close-minded. He's not abnormal, he's special. 306 00:17:20,239 --> 00:17:23,675 Cerebral cortex atrophies in coma patients. 307 00:17:25,577 --> 00:17:28,239 You need Iive, conscious people. 308 00:17:31,917 --> 00:17:34,351 You don't know everything, House! 309 00:17:38,424 --> 00:17:41,154 FOREMAN: Something that disrupts brain function. 310 00:17:41,427 --> 00:17:44,863 PIaques are perfect. Interrupt neuronal communication. 311 00:17:44,930 --> 00:17:47,262 MS? No, MS is complicated. 312 00:17:47,332 --> 00:17:51,166 I think this is more basic. It's just tachycardia and seizures. 313 00:17:51,236 --> 00:17:54,296 How much Ionger the Burn Unit guys gonna keep him in that thing? 314 00:17:54,373 --> 00:17:57,274 Lecture's over, Iet's go. House wants to... 315 00:18:00,179 --> 00:18:01,840 Adam's waking up. 316 00:18:02,247 --> 00:18:04,044 Get the anesthesiologist in here now. 317 00:18:04,116 --> 00:18:05,413 CAMERON: He's in pain. 318 00:18:07,019 --> 00:18:08,884 That's not pain. 319 00:18:09,621 --> 00:18:11,555 Need some help in here! 320 00:19:13,452 --> 00:19:15,215 Adam had an orgasm. 321 00:19:17,022 --> 00:19:19,820 What? You mean, while he was sedated... 322 00:19:21,860 --> 00:19:22,849 (HOUSE EXCLAIMING) 323 00:19:26,365 --> 00:19:27,832 What's wrong? 324 00:19:29,401 --> 00:19:31,369 I'm having a migraine. 325 00:19:31,770 --> 00:19:33,237 Are you okay? 326 00:19:34,773 --> 00:19:35,865 Yes. 327 00:19:37,643 --> 00:19:39,076 I was right. 328 00:19:41,213 --> 00:19:42,202 (GROANING) 329 00:19:49,888 --> 00:19:52,015 I'm gonna knock you out for a couple of hours. 330 00:19:52,090 --> 00:19:53,887 No, I got work to do. 331 00:19:54,259 --> 00:19:57,092 Just give me sumatriptan for the pain 332 00:19:57,162 --> 00:19:59,653 and verapamil so it doesn't recur. 333 00:20:03,335 --> 00:20:06,930 I heard the patient had fun in the hyperbaric chamber. 334 00:20:07,005 --> 00:20:08,131 Yeah. 335 00:20:08,207 --> 00:20:10,801 Gotta schedule me some time in there. 336 00:20:13,478 --> 00:20:16,311 Weber's meds aren't even Iegal in the U.S. 337 00:20:16,548 --> 00:20:18,311 It's Iegal in India. 338 00:20:19,751 --> 00:20:21,446 I was disoriented. 339 00:20:27,359 --> 00:20:29,520 Moving around is a bad idea. 340 00:20:29,895 --> 00:20:32,557 Hey, if you feel chest pain, you need to Iet me know. 341 00:20:32,631 --> 00:20:35,566 Verapamil can cause congestive heart failure. 342 00:20:35,701 --> 00:20:37,726 Nothing can hurt my heart. 343 00:20:40,839 --> 00:20:45,173 Hey, you're gonna feel some dizziness. Definitely gonna be constipated. 344 00:20:49,748 --> 00:20:53,582 Differential diagnosis for getting off. 345 00:20:54,386 --> 00:20:57,753 Is he gonna be okay? No. Something's seriously wrong with him. 346 00:20:57,823 --> 00:21:02,385 Differential diagnosis for ejaculation. 347 00:21:04,763 --> 00:21:06,390 Don't make me say it again. 348 00:21:06,465 --> 00:21:08,626 We're not stalling, we just don't know. 349 00:21:08,700 --> 00:21:10,065 Then guess. 350 00:21:10,869 --> 00:21:13,667 Could pain medication cause an orgasm? I wish. 351 00:21:13,739 --> 00:21:15,707 Maybe pain caused the orgasm. 352 00:21:15,774 --> 00:21:19,210 You get a tattoo, the brain releases endorphins which create pleasure. 353 00:21:19,278 --> 00:21:21,838 Most people don't orgasm from a needle prick. 354 00:21:21,913 --> 00:21:23,778 HOUSE: Well, Chase has a point. 355 00:21:23,849 --> 00:21:27,546 The brain is Iike a huge train station, if the switches... 356 00:21:28,453 --> 00:21:29,442 (GROANING) 357 00:21:30,856 --> 00:21:32,824 You're the neurologist, talk for me. 358 00:21:32,891 --> 00:21:36,987 If sensory information got misinterpreted by the medial forebrain bundle, 359 00:21:37,062 --> 00:21:39,997 it's possible for bad to feel good, and good to feel bad. 360 00:21:40,065 --> 00:21:43,728 He's a Iucky kid. Let's not fix him until the burns heal. 361 00:21:43,802 --> 00:21:45,861 So what attacks the medial forebrain bundle? 362 00:21:45,937 --> 00:21:48,201 Infective neuropathies, vasculitic neuropathies... 363 00:21:48,273 --> 00:21:50,400 Krabbe's disease, metachromatic Ieukodystrophy. 364 00:21:50,475 --> 00:21:53,205 HOUSE: AII very bad things. 365 00:21:53,278 --> 00:21:55,906 No way to Iook for any of them in his condition. 366 00:21:55,981 --> 00:21:57,346 Could be an infection. 367 00:21:57,416 --> 00:21:59,077 I said infection about eight seconds ago. 368 00:21:59,151 --> 00:22:01,119 You Iisted some brain infections. 369 00:22:01,186 --> 00:22:05,680 But what if it's just a regular old infection festering in the burned skin? 370 00:22:05,757 --> 00:22:08,282 Pus on his arm isn't causing problems in the forebrain. 371 00:22:08,360 --> 00:22:11,921 He's on 20 different medications to manage his pain, his heart, 372 00:22:11,997 --> 00:22:13,658 how often he urinates. 373 00:22:13,732 --> 00:22:16,360 His brain is Iike a waiter that's got too many... 374 00:22:16,435 --> 00:22:19,165 Hey, hey. I do the metaphors. 375 00:22:21,206 --> 00:22:22,798 The brain is stressed. 376 00:22:22,874 --> 00:22:25,069 An infection elsewhere could put it over the edge. 377 00:22:25,143 --> 00:22:28,237 So we just wait for his burns to heal to see if you're right? 378 00:22:28,313 --> 00:22:31,578 If you're wrong, he doesn't have that kind of time. 379 00:22:33,018 --> 00:22:34,576 Dominic Larrey. 380 00:22:35,454 --> 00:22:37,479 He another dead doctor? 381 00:22:37,556 --> 00:22:40,218 He's Napoleon's Surgeon in Chief. 382 00:22:40,292 --> 00:22:41,850 CIeaned a Iot of battle wounds. 383 00:22:41,927 --> 00:22:43,326 By amputating Iegs. 384 00:22:43,395 --> 00:22:45,056 And with bugs. 385 00:22:49,835 --> 00:22:53,032 CAMERON: Maggots are implanted directly into Adam's burns. 386 00:22:53,872 --> 00:22:56,864 Maggots, they eat dead people, I... 387 00:22:56,942 --> 00:23:00,400 Maggots eat dead flesh. Only dead flesh. 388 00:23:00,946 --> 00:23:03,881 So they're perfectly suited to clean wounds. 389 00:23:04,750 --> 00:23:08,117 They also kill the bacteria that thrive in injured tissues. 390 00:23:38,183 --> 00:23:39,309 (EXCLAIMING) 391 00:23:45,891 --> 00:23:47,188 Dr. Jekyll, I presume. 392 00:23:47,259 --> 00:23:50,922 They found a half-eaten sheep in the zoo. The police wanna ask you a few questions. 393 00:23:50,996 --> 00:23:52,588 I need something to wash it down. 394 00:23:52,664 --> 00:23:54,723 Coffee? Bad idea. 395 00:23:54,800 --> 00:23:57,894 You're better off with water! Coffee's closer. 396 00:23:59,871 --> 00:24:01,771 Foolproof plan, by the way. 397 00:24:01,840 --> 00:24:03,637 Either his meds would work, 398 00:24:03,708 --> 00:24:08,338 and you'd be in psychic pain because Von Evil is gonna be rich. 399 00:24:09,381 --> 00:24:13,078 Or they wouldn't, and you get to be in agony all day. 400 00:24:14,219 --> 00:24:17,188 Perfect Iose-Iose situation. Very you. 401 00:24:17,255 --> 00:24:20,088 I had to prove... You've proved nothing. 402 00:24:22,594 --> 00:24:25,461 Right. This isn't a migraine. 403 00:24:26,264 --> 00:24:28,391 Yeah. "Dear New England Journal of Medicine, 404 00:24:28,467 --> 00:24:31,163 "I took this guy's drug and still got a headache. 405 00:24:31,236 --> 00:24:34,899 "Thus, scientifically proving that my arch enemy is an idiot." 406 00:24:34,973 --> 00:24:36,304 You just wanted the pain. 407 00:24:36,374 --> 00:24:39,866 Meds are supposed to prevent migraine. 408 00:24:39,945 --> 00:24:41,572 You get distracted by pain. 409 00:24:41,646 --> 00:24:44,410 Leaves Iess room for the things you don't wanna think about. 410 00:24:44,483 --> 00:24:47,782 Like the FIyers sucking, or the price of gas, 411 00:24:48,119 --> 00:24:51,316 or the fact that you pushed the Iove of your Iife out of your Iife. 412 00:24:51,389 --> 00:24:54,187 God, I wish the pain would go away. 413 00:24:54,526 --> 00:24:57,359 Next time you need to get your mind off her, stick a needle in your eye. 414 00:24:57,429 --> 00:25:01,229 It's Iess annoying to the rest of us when you can still walk. 415 00:25:08,406 --> 00:25:10,135 CAMERON: Did you sleep here? 416 00:25:13,879 --> 00:25:15,039 Lower. 417 00:25:15,981 --> 00:25:17,539 Do you want a pillow? 418 00:25:18,550 --> 00:25:20,211 Not softer, Iower. 419 00:25:21,019 --> 00:25:23,419 Frequency of your voice is grating. 420 00:25:23,488 --> 00:25:25,217 You should've been better by now. 421 00:25:25,323 --> 00:25:26,813 I'm super. 422 00:25:27,225 --> 00:25:28,522 Patient? 423 00:25:29,060 --> 00:25:31,551 The maggots did great for the burn. 424 00:25:31,897 --> 00:25:33,990 But the brain waves are still all over the map. 425 00:25:34,065 --> 00:25:38,297 Which means your regular old infection isn't causing his brain dysfunction. 426 00:25:38,370 --> 00:25:40,235 Which means there's an underlying condition, 427 00:25:40,305 --> 00:25:43,035 which means we've gotta get inside his head. 428 00:25:43,108 --> 00:25:44,905 Do a Iumbar puncture. 429 00:25:44,976 --> 00:25:47,206 We've already established that we can't get a Iumbar... 430 00:25:47,279 --> 00:25:49,270 C2, C3. 431 00:25:49,347 --> 00:25:51,338 No. No. No way. 432 00:25:51,950 --> 00:25:55,408 I only saw a cervical tap once, and that guy got paralyzed. 433 00:25:55,487 --> 00:25:59,924 Ask the parents if they prefer to have their son in a wheelchair or dead. 434 00:26:04,396 --> 00:26:07,297 Something's causing his brain to Iose control. 435 00:26:07,365 --> 00:26:09,265 Eventually it'II shut off. 436 00:26:09,334 --> 00:26:10,858 We need to do a Iumbar puncture 437 00:26:10,936 --> 00:26:13,803 to get some of the fluid in his spine so we can test it. 438 00:26:13,872 --> 00:26:16,033 You need us to sign a consent? 439 00:26:16,107 --> 00:26:17,836 I have to warn you. 440 00:26:17,909 --> 00:26:20,901 There's a serious risk of paralysis or death. 441 00:26:21,846 --> 00:26:23,643 Are you saying we shouldn't do this? 442 00:26:24,316 --> 00:26:25,544 You have to do this. 443 00:26:25,617 --> 00:26:27,482 Then why are you telling us what can go wrong? 444 00:26:27,552 --> 00:26:29,645 I just think you should know... Either you're cruel 445 00:26:29,721 --> 00:26:31,621 or this clipboard is a way for you to cover your ass, 446 00:26:31,690 --> 00:26:33,453 in case you cripple our son. This isn't his fault. 447 00:26:33,525 --> 00:26:36,585 No, it's not. It's yours, that's what you keep telling me. 448 00:26:36,661 --> 00:26:38,288 My son is Iying in there half-dead, 449 00:26:38,363 --> 00:26:41,594 I am just trying to find a way to get through this. 450 00:26:41,666 --> 00:26:43,998 I'm sorry. Yeah, I know. 451 00:26:47,539 --> 00:26:48,733 (MONITOR BEEPING) 452 00:27:03,788 --> 00:27:04,982 Needle. 453 00:27:20,338 --> 00:27:22,829 It's not going in. Don't force it. 454 00:27:23,274 --> 00:27:24,502 I'm going one space higher. 455 00:27:24,576 --> 00:27:27,773 It's too close to his brain stem, it'II herniate. 456 00:27:28,013 --> 00:27:31,141 You're gonna paralyze him. You're not helping. 457 00:27:31,316 --> 00:27:33,876 His blood pressure's spiking, stop. I can get it. 458 00:27:33,952 --> 00:27:36,580 (MONITOR BEEPING RAPIDLY) He's 180 over 1 20, he's gonna stroke. 459 00:27:38,256 --> 00:27:40,747 I'm in the space. Give me the vial. 460 00:27:50,568 --> 00:27:52,433 (MONITOR BEEPING RHYTHMICALLY) 461 00:27:58,276 --> 00:28:00,767 He doesn't have MS or an infection. 462 00:28:02,681 --> 00:28:05,047 His proteins aren't elevated? 463 00:28:05,116 --> 00:28:07,778 Wrong protein. IgM, not IgG. 464 00:28:08,053 --> 00:28:10,954 EIevation was probably caused by the bleed. 465 00:28:12,257 --> 00:28:16,284 What if there was tingling in his extremities prior to the crash? 466 00:28:16,928 --> 00:28:20,386 How can you still be on MS? I gotta be on something. 467 00:28:21,066 --> 00:28:24,900 Something's interrupting his neurons' chitchat, Iike Iesions. 468 00:28:24,969 --> 00:28:26,732 We can't scan for them. 469 00:28:26,805 --> 00:28:29,968 The only test we can do, we just did and it was negative. 470 00:28:30,041 --> 00:28:32,100 He has no tingling, no numbness. 471 00:28:32,177 --> 00:28:34,645 And you read his history, parents didn't say anything about... 472 00:28:34,713 --> 00:28:36,305 What about Adam? 473 00:28:37,682 --> 00:28:41,584 We can't Iook into his brain, but you want us to read his mind? 474 00:28:42,520 --> 00:28:43,919 Good point. 475 00:28:49,227 --> 00:28:50,285 (DOOR OPENING) 476 00:28:53,398 --> 00:28:55,958 Yeah, you can finish the sponge bath in a minute. 477 00:28:56,034 --> 00:28:59,401 They're just re-doing his dressings. He's out, he's fine. 478 00:28:59,471 --> 00:29:03,305 I didn't page you to put him out. I paged you to wake him up. 479 00:29:03,441 --> 00:29:06,001 Why are these Iights so damn bright? 480 00:29:06,478 --> 00:29:07,843 Thank you. 481 00:29:07,912 --> 00:29:09,903 Come on, I need to talk to him. 482 00:29:09,981 --> 00:29:12,677 House, you can't wake up a burn victim to play twenty questions. 483 00:29:12,751 --> 00:29:14,719 It's torture. He won't remember. 484 00:29:14,786 --> 00:29:17,448 He's gonna be in extraordinary... God, you're good! 485 00:29:17,522 --> 00:29:19,319 You're putting me to sleep. 486 00:29:19,390 --> 00:29:22,951 I know he's gonna be in pain, I know you disapprove. I'm his attending. 487 00:29:23,027 --> 00:29:24,426 Wake him up. 488 00:29:41,679 --> 00:29:43,840 (GASPING) 489 00:29:43,915 --> 00:29:45,405 Oh, my God! 490 00:29:45,483 --> 00:29:47,815 I'm Dr. House. It hurts! 491 00:29:48,153 --> 00:29:50,121 It's gonna get a Iot worse, so answer fast. 492 00:29:50,188 --> 00:29:54,887 Before the accident, did you experience any numbness or tingling in your fingers? 493 00:29:54,959 --> 00:29:57,450 You got burned, it's healing, I need an answer. 494 00:29:57,529 --> 00:29:58,723 It really hurts! 495 00:29:58,797 --> 00:30:00,697 Any tingling in your arms or Iegs? 496 00:30:00,765 --> 00:30:02,460 You gotta do something, I can't... 497 00:30:02,534 --> 00:30:05,867 Adam, you gotta Iisten to me, did you feel anything? 498 00:30:05,970 --> 00:30:07,403 (CRYING IN PAIN) 499 00:30:07,472 --> 00:30:12,068 I pissed in my pants and then I don't remember... 500 00:30:14,479 --> 00:30:17,004 (SCREAMING IN PAIN) 501 00:30:51,382 --> 00:30:54,146 Was he okay? Get everyone in my office. 502 00:30:55,253 --> 00:30:56,880 Where you going? 503 00:30:57,255 --> 00:31:01,021 Kid's screaming gave me a headache. I gotta take an aspirin. 504 00:32:00,118 --> 00:32:03,281 House, you okay? We've been waiting for you. 505 00:32:07,992 --> 00:32:09,653 I'm hallucinating. 506 00:32:13,031 --> 00:32:16,228 Hallucinations with migraines are pretty uncommon. 507 00:32:17,001 --> 00:32:20,266 What did you see? I saw music. 508 00:32:22,206 --> 00:32:24,640 Sensory deception makes no sense. 509 00:32:28,947 --> 00:32:30,710 You took something. 510 00:32:31,616 --> 00:32:33,982 The kid's fighting for his Iife. 511 00:33:03,247 --> 00:33:04,509 Hey, you find him? 512 00:33:04,582 --> 00:33:06,675 He was hallucinating in the Iocker room. 513 00:33:06,751 --> 00:33:08,150 He okay? 514 00:33:08,219 --> 00:33:10,016 He's feeling no pain, he's high. 515 00:33:10,088 --> 00:33:11,385 Vicodin high? 516 00:33:11,456 --> 00:33:14,050 Past that. He's seeing sounds. 517 00:33:14,325 --> 00:33:15,883 Took something. 518 00:33:18,763 --> 00:33:21,425 Why is it so dark in here? It's a beautiful day outside. 519 00:33:21,499 --> 00:33:24,127 Open the shades, Iet the sun shine in. 520 00:33:24,202 --> 00:33:25,760 It's nighttime. 521 00:33:27,605 --> 00:33:30,574 It's still Tuesday, right? You Iook better. 522 00:33:30,942 --> 00:33:33,570 I took something. Mind if I ask what? 523 00:33:34,979 --> 00:33:37,243 Little of this, Iittle of that. 524 00:33:37,315 --> 00:33:39,306 I know what's wrong with our patient. 525 00:33:39,384 --> 00:33:40,908 He's depressed. 526 00:33:40,985 --> 00:33:42,680 He told you that when you woke him up? Nope. 527 00:33:42,754 --> 00:33:44,517 He told me he pissed his pants and blacked out. 528 00:33:44,589 --> 00:33:47,786 That's not diagnostic of depression. Lack of appetite, isolating yourself. 529 00:33:47,859 --> 00:33:50,987 Uncontrollable urination and blacking out are good predictors of what? 530 00:33:51,062 --> 00:33:52,120 Seizure. 531 00:33:52,196 --> 00:33:54,630 Which means the seizure he had when you tested his heart 532 00:33:54,699 --> 00:33:56,667 was at Ieast his second seizure. So what? 533 00:33:56,734 --> 00:34:01,137 Depression and seizures aren't correlated. No, but you know what is? 534 00:34:01,205 --> 00:34:03,799 Depression and anti-depression medicine. 535 00:34:03,875 --> 00:34:05,433 Tox screen was clean. 536 00:34:05,510 --> 00:34:07,705 Yeah, but you know how much crap he's got in his system 537 00:34:07,779 --> 00:34:08,939 for dealing with those burns. 538 00:34:09,013 --> 00:34:11,982 The guy could have the Spanish Armada floating through his bloodstream 539 00:34:12,050 --> 00:34:14,644 and we wouldn't know about it, till they started firing cannons. 540 00:34:14,719 --> 00:34:18,314 Antidepressants have been known to cause seizures in kids, but not orgasms. 541 00:34:18,389 --> 00:34:22,553 This is a brain in trouble. This is a brain with too much serotonin. 542 00:34:22,627 --> 00:34:26,427 Serotonin affects mood, appetite, it doesn't cause the brain to shut down. 543 00:34:26,497 --> 00:34:29,625 Antidepressants fake brains into thinking they have more serotonin 544 00:34:29,700 --> 00:34:31,031 than they actually do. 545 00:34:31,102 --> 00:34:34,833 Every ten million or so cases sets off a chain reaction. 546 00:34:34,906 --> 00:34:37,534 Produces too much, enough to fry itself. 547 00:34:37,608 --> 00:34:39,974 If Adam has Serotonin Storm, it's deadly. 548 00:34:40,044 --> 00:34:42,274 But treatable. Cyproheptadine. 549 00:34:42,346 --> 00:34:43,904 Unless he doesn't have Serotonin Storm. 550 00:34:43,981 --> 00:34:46,609 He could just as easily have too much dopamine as serotonin, 551 00:34:46,684 --> 00:34:50,245 but if it's dopamine, the cyproheptadine will kill him. 552 00:34:50,321 --> 00:34:53,290 Where are you going? Gonna talk to the kid again, he seems nice. 553 00:34:53,357 --> 00:34:54,722 You can't. 554 00:34:55,126 --> 00:34:56,616 Why? Did he say he doesn't Iike me? 555 00:34:56,694 --> 00:34:59,822 Anesthesiologist told the parents what you did. 556 00:34:59,897 --> 00:35:01,888 Everyone's a tattletale. 557 00:35:08,339 --> 00:35:10,204 Is your son depressed? 558 00:35:11,776 --> 00:35:14,244 No. Who are you? I'm Dr. House. 559 00:35:14,312 --> 00:35:15,574 Oh, you're the idiot who thought... 560 00:35:15,646 --> 00:35:17,443 I heard him screaming all the way down the hallway. 561 00:35:17,515 --> 00:35:20,382 If I didn't wake him up, I wouldn't have Iearned what caused the crash. 562 00:35:20,451 --> 00:35:22,078 He had a seizure. 563 00:35:25,456 --> 00:35:27,287 This wasn't my fault? 564 00:35:28,326 --> 00:35:31,489 Well, if he hadn't had the brain problem, he wouldn't have the burns. 565 00:35:31,562 --> 00:35:33,655 On the other hand, if you hadn't put him on the ATV, 566 00:35:33,731 --> 00:35:34,959 he also wouldn't have the burns. 567 00:35:35,032 --> 00:35:37,193 You can debate your personal responsibility after I Ieave. 568 00:35:37,268 --> 00:35:38,758 I need to wake him up again. 569 00:35:38,836 --> 00:35:40,667 I need to know if he's taking antidepressants. 570 00:35:40,738 --> 00:35:42,000 He's not. 571 00:35:42,840 --> 00:35:46,571 He's the happiest kid I know. But you don't know, do you? 572 00:35:48,746 --> 00:35:50,145 He's my son. 573 00:35:50,715 --> 00:35:52,376 That's sort of my point. 574 00:35:52,450 --> 00:35:55,851 At 16, they'II tell anyone anything, except their parents. 575 00:35:55,920 --> 00:35:57,615 Adam talks to us about everything. 576 00:35:57,688 --> 00:35:59,747 Yeah, I know about the pot and the cocaine. 577 00:35:59,824 --> 00:36:01,689 There was never... Cocaine. What... 578 00:36:01,759 --> 00:36:04,853 Are you sure? Are you having him followed? 579 00:36:04,929 --> 00:36:07,523 He told us when he got drunk at a party. 580 00:36:07,598 --> 00:36:09,429 He told us when he started having sex. 581 00:36:09,500 --> 00:36:11,195 At 16? Way to go. 582 00:36:11,269 --> 00:36:12,998 He told us when he cheated on a math test. 583 00:36:13,070 --> 00:36:15,300 He told us when his girlfriend cheated on him. 584 00:36:15,373 --> 00:36:18,342 He doesn't hide anything from us. But if he was depressed? 585 00:36:18,409 --> 00:36:19,899 He'd tell us. 586 00:36:20,111 --> 00:36:23,046 We don't judge, he's not depressed, we're sure. 587 00:36:23,114 --> 00:36:25,241 "Bet his Iife on it" sure? 588 00:36:26,918 --> 00:36:28,715 Just hypothetically. 589 00:36:30,288 --> 00:36:31,380 Yeah. 590 00:36:34,926 --> 00:36:36,018 Okay. 591 00:36:38,863 --> 00:36:40,296 Kid's happy. 592 00:36:41,232 --> 00:36:43,257 Happy, happy, happy. 593 00:36:43,568 --> 00:36:46,969 Then we're back to where we started. Seizure disorders. 594 00:36:47,038 --> 00:36:49,939 Seizure disorders aren't causing orgasms. 595 00:36:50,007 --> 00:36:51,634 Vascular malformations? 596 00:36:51,709 --> 00:36:53,768 Would've seen it on the sonogram. 597 00:36:53,844 --> 00:36:55,903 Hepatic encephalopathy? 598 00:36:55,980 --> 00:36:58,278 Liver enzyme tests were normal. 599 00:37:04,188 --> 00:37:06,656 Where are you going? Take a Ieak. 600 00:37:14,732 --> 00:37:15,858 What are you doing? 601 00:37:15,933 --> 00:37:17,924 You can't come in here, you're not sterile. 602 00:37:18,002 --> 00:37:19,401 Don't touch our son, we told you... 603 00:37:19,470 --> 00:37:22,064 Seriously, millions of bacteria, microbes on you. 604 00:37:22,139 --> 00:37:25,074 He'II die of sepsis. If you go in there... 605 00:37:28,913 --> 00:37:30,471 I think he's gonna wake him up again. 606 00:37:30,548 --> 00:37:32,106 I know he is. 607 00:37:33,884 --> 00:37:35,681 House, you can't do this. 608 00:37:35,753 --> 00:37:39,883 Oh, if I had a nickel for every time I've heard that. Relax. 609 00:37:39,957 --> 00:37:43,586 Are they gonna sue us? If I'm right, I save his Iife. 610 00:37:43,661 --> 00:37:46,630 If I'm wrong, he's dead no matter what I do. 611 00:37:46,964 --> 00:37:49,933 Either way, how much have I really hurt them? 612 00:37:50,001 --> 00:37:51,263 Leave him alone! 613 00:37:51,335 --> 00:37:53,735 You're not sterile. Do you wanna kill the kid? 614 00:37:53,804 --> 00:37:55,772 Give me the syringe. No pain, no gain. 615 00:37:55,840 --> 00:37:57,831 Hey, you gotta stop this. 616 00:38:02,013 --> 00:38:03,480 They're right. 617 00:38:04,348 --> 00:38:07,078 He's not depressed. FOREMAN: Yeah, sure. 618 00:38:07,151 --> 00:38:09,779 I'm not Ietting you go till you give me that syringe. 619 00:38:09,854 --> 00:38:11,845 What's that on his wrist? 620 00:38:12,923 --> 00:38:14,151 A burn. 621 00:38:14,225 --> 00:38:16,557 Why on his wrist? Why not on his wrist? 622 00:38:16,627 --> 00:38:20,529 His back, his torso, everything's a mess. His forearms are clean. 623 00:38:20,598 --> 00:38:22,793 Except right there. So what? 624 00:38:24,235 --> 00:38:25,600 It's a perfect circle. 625 00:38:25,670 --> 00:38:29,970 So a drop of burning gasoline fell on his wrist, a screw from the ATV. 626 00:38:30,708 --> 00:38:31,868 Maybe. 627 00:38:41,952 --> 00:38:44,853 Why are you torturing him? Does your son smoke? 628 00:38:46,157 --> 00:38:47,624 I'd kill him. 629 00:38:49,627 --> 00:38:53,996 So, he can talk to you about sex, crack, anything except cigarettes. 630 00:38:55,232 --> 00:38:57,826 He has a cigarette burn on his wrist. 631 00:38:58,436 --> 00:39:01,633 AIso a fading nicotine stain between two fingers. 632 00:39:02,440 --> 00:39:05,637 Bad news, your son has a filthy, unhealthy habit. 633 00:39:05,710 --> 00:39:08,076 Good news, he's trying to quit. 634 00:39:08,145 --> 00:39:10,272 Bad news, the quitting's killing him. 635 00:39:10,348 --> 00:39:13,146 Good news, I can cure him. Bad news... 636 00:39:14,618 --> 00:39:16,848 Nope, that's the end of it. 637 00:39:16,921 --> 00:39:18,912 Quitting smoking can kill? 638 00:39:18,989 --> 00:39:21,219 No-smoke meds are antidepressants. 639 00:39:21,292 --> 00:39:23,351 The crappy ones you get over the Internet 640 00:39:23,427 --> 00:39:26,225 are Ioaded with whatever antidepressants they can get cheap. 641 00:39:26,297 --> 00:39:30,597 And since Mommy and Daddy obviously didn't take him to a pediatrician... 642 00:39:32,970 --> 00:39:35,939 Sorry, I was wrong about him being depressed. 643 00:39:36,540 --> 00:39:37,871 Treat him. 644 00:39:54,959 --> 00:39:55,983 (DOOR OPENING) 645 00:39:56,060 --> 00:39:57,152 CUDDY: Hey! 646 00:39:58,262 --> 00:40:00,423 Did you drop acid? 647 00:40:02,133 --> 00:40:05,000 Why would I do that? To annoy me. 648 00:40:05,136 --> 00:40:07,502 Or maybe because you're miserable, 649 00:40:07,571 --> 00:40:10,870 or because you want to self-destruct. 650 00:40:11,208 --> 00:40:12,505 Pick one. 651 00:40:12,977 --> 00:40:16,936 How about because LSD acts on serotonin receptors in the brain, 652 00:40:17,014 --> 00:40:19,812 which can stop a migraine in its tracks. 653 00:40:20,351 --> 00:40:22,819 I'm just saying that's also a possibility. 654 00:40:22,887 --> 00:40:26,323 How did you know about it? Cameron is worried about you. 655 00:40:26,390 --> 00:40:30,292 I told her that LSD Iasts up to 1 2 hours, if you were functional, she must be wrong. 656 00:40:30,361 --> 00:40:33,194 Either that or I also took a whole bunch of antidepressants, 657 00:40:33,264 --> 00:40:35,357 which short-circuited the LSD. 658 00:40:35,433 --> 00:40:37,264 I'm just saying that would also explain it. 659 00:40:37,334 --> 00:40:39,632 Thank you for ruining my clinical trials. 660 00:40:39,703 --> 00:40:41,694 Pharmaceutical company's shutting me down. 661 00:40:41,772 --> 00:40:44,002 You're kidding. Really? How could that surprise you? 662 00:40:44,074 --> 00:40:45,268 You sent them an email 663 00:40:45,342 --> 00:40:47,902 complaining about my math, telling them about your stunt. 664 00:40:47,978 --> 00:40:50,173 I didn't know people actually read emails. 665 00:40:50,247 --> 00:40:52,977 Delete button's so conveniently Iocated. So what's next? 666 00:40:53,083 --> 00:40:54,607 You gonna follow me my whole Iife? 667 00:40:54,685 --> 00:40:56,482 Torture me? Why would I do that? 668 00:40:56,554 --> 00:41:00,650 You waited 20 years to do this. What's next? Break up my marriage? 669 00:41:01,492 --> 00:41:04,757 No. We're even. Right. 670 00:41:06,864 --> 00:41:09,059 Oh, thanks for setting me up. 671 00:41:12,770 --> 00:41:16,137 Eye for an eye, LSD and antidepressants. 672 00:41:16,941 --> 00:41:18,772 Everything in balance. 673 00:41:18,843 --> 00:41:21,903 Buddhists call it Karma. Christians call it the Golden Rule. 674 00:41:21,979 --> 00:41:23,571 Jews call it... 675 00:41:25,616 --> 00:41:28,881 I don't know, Rabbi Hillel said something poignant. 676 00:41:30,254 --> 00:41:32,688 Universe always settles the score. 677 00:41:33,524 --> 00:41:35,992 Does it? No. 678 00:41:37,895 --> 00:41:39,419 But it should. 679 00:41:47,137 --> 00:41:51,130 Do you think you'II ever be able to Iook at him and not blame me? 680 00:41:52,042 --> 00:41:55,068 Yeah. Will you? 681 00:42:24,642 --> 00:42:25,802 (KNOCKING AT DOOR) 682 00:42:46,864 --> 00:42:48,195 PAULA: I'm Paula. 683 00:42:48,465 --> 00:42:51,059 Hey, Paula. How you doing? 684 00:42:52,603 --> 00:42:55,629 You work over at the college, or are you full-time over at the... 685 00:42:55,706 --> 00:42:57,970 I'm Iooking for a distraction. 686 00:42:58,742 --> 00:43:01,575 You don't need to talk to do that, do you?